2005年获美国迈阿密大学化学系有机化学专业博士学位 (Ph.D.)
2005-2006年美国迈阿密大学化学系博士后
2005-2006年美国迈阿密大学化学系博士后
1.具有抗纤维化或抗肿瘤活性的天然产物的合成、结构修饰及活性评价;
2.药物新合成路线的设计与开发。
2.药物新合成路线的设计与开发。
1. Dongsheng Chen, Yaping Song, Yunlong Lu, and Xiaowen Xue*, “Synthesis and in vitro cytotoxicity of andrographolide-19-oic acid analogues as anti-cancer agents”, Bioorg. & Med. Chem. Lett. 2013, 23, 3166-3169.
2. Qiao Sun, Yiwu Yao, Chunping Liu, Hua Li, Hequan Yao, Xiaowen Xue, Jinsong Liu, Zhengchao Tu, Sheng Jiang, “Design, synthesis, and biological evaluation of novel histone deacetylase 1 inhibitors through click chemistry”, Bioorg. & Med. Chem. Lett. 2013, 23, 3295-3299.
3. Lutai Wang，Jiabin Li, Xiaowen Xue*, “A Concise Synthesis of Ximenynic Acid”, Synth. Commun. 2012, 42, 3540-3543.
4. Lei Yang, Xiaowen Xue*, Yihua Zhang, “Simple and Efficient Synthesis of Belinostat”, Synth. Commun. 2010, 40, 2520-2524.
5. Xueqing Zhao, Fei Li, Weiping Zhuang, Xiaowen Xue*，Yuanyang Lian, Jianhui Fan, Dongsheng Fang,“A New Method for Synthesis of Nolatrexed Dihydrochloride”, Org. Process Res. Dev. 2010, 14, 346-350.
6. Xueqing Zhao*, Weiping Zhuang, Dongsheng Fang, Xiaowen Xue*, Jingming Zhou, “A Highly Efficient Conversion of Primary or Secondary Alcohols into Fluorides with n-Perfluorobutanesulfonyl Fluoride-Tetrabutylammonium Triphenyldifluorosilicate”, Synlett 2009, 779-782.
7. Benjamin W. Gung*, Xiaowen Xue and Zou Yan, “Enthalpy (H) and Entropy (S) for π-Stacking Interactions in Near-Sandwich Configurations: Relative Importance of Electrostatic, Dispersive, and Charge-Transfer Effects”, J. Org. Chem. 2007, 72，2469-2475.
8. Benjamin W. Gung*, Xiaowen Xue and Hans J. Reich, “Off Center Oxygen-Arene Interactions in Solution: A Quantitative Study”, J. Org. Chem. 2005, 70, 7232-7237.
9. Benjamin W. Gung*, Xiaowen Xue and Hans J. Reich, “The Strength of Parallel- Displaced Arene-Arene Interactions in Chloroform”, J. Org. Chem. 2005, 70, 3641-3644.
10. Benjamin W. Gung,* Xiaowen Xue, and William R. Roush, “The origin of diastereofacial control in allyboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen”, J. Am. Chem. Soc. 2002, 124, 10692.
2. Qiao Sun, Yiwu Yao, Chunping Liu, Hua Li, Hequan Yao, Xiaowen Xue, Jinsong Liu, Zhengchao Tu, Sheng Jiang, “Design, synthesis, and biological evaluation of novel histone deacetylase 1 inhibitors through click chemistry”, Bioorg. & Med. Chem. Lett. 2013, 23, 3295-3299.
3. Lutai Wang，Jiabin Li, Xiaowen Xue*, “A Concise Synthesis of Ximenynic Acid”, Synth. Commun. 2012, 42, 3540-3543.
4. Lei Yang, Xiaowen Xue*, Yihua Zhang, “Simple and Efficient Synthesis of Belinostat”, Synth. Commun. 2010, 40, 2520-2524.
5. Xueqing Zhao, Fei Li, Weiping Zhuang, Xiaowen Xue*，Yuanyang Lian, Jianhui Fan, Dongsheng Fang,“A New Method for Synthesis of Nolatrexed Dihydrochloride”, Org. Process Res. Dev. 2010, 14, 346-350.
6. Xueqing Zhao*, Weiping Zhuang, Dongsheng Fang, Xiaowen Xue*, Jingming Zhou, “A Highly Efficient Conversion of Primary or Secondary Alcohols into Fluorides with n-Perfluorobutanesulfonyl Fluoride-Tetrabutylammonium Triphenyldifluorosilicate”, Synlett 2009, 779-782.
7. Benjamin W. Gung*, Xiaowen Xue and Zou Yan, “Enthalpy (H) and Entropy (S) for π-Stacking Interactions in Near-Sandwich Configurations: Relative Importance of Electrostatic, Dispersive, and Charge-Transfer Effects”, J. Org. Chem. 2007, 72，2469-2475.
8. Benjamin W. Gung*, Xiaowen Xue and Hans J. Reich, “Off Center Oxygen-Arene Interactions in Solution: A Quantitative Study”, J. Org. Chem. 2005, 70, 7232-7237.
9. Benjamin W. Gung*, Xiaowen Xue and Hans J. Reich, “The Strength of Parallel- Displaced Arene-Arene Interactions in Chloroform”, J. Org. Chem. 2005, 70, 3641-3644.
10. Benjamin W. Gung,* Xiaowen Xue, and William R. Roush, “The origin of diastereofacial control in allyboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen”, J. Am. Chem. Soc. 2002, 124, 10692.
